ICA

TargetMol
Product Code: TAR-T15546
Supplier: TargetMol
CodeSizePrice
TAR-T15546-1mg1mg£189.00
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Quantity:
TAR-T15546-1mL1 mL * 10 mM (in DMSO)£405.00
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Quantity:
TAR-T15546-5mg5mg£430.00
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Quantity:
TAR-T15546-10mg10mg£600.00
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Quantity:
TAR-T15546-25mg25mg£863.00
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Quantity:
TAR-T15546-50mg50mg£1,187.00
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Quantity:
TAR-T15546-100mg100mg£1,581.00
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Quantity:
TAR-T15546-500mg500mg£3,107.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
ICA is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 ?M).
CAS:
3374-88-7
Formula:
C13H10N4S
Molecular Weight:
254.31
Pathway:
Membrane transporter/Ion channel; Microbiology/Virology
Purity:
0.98
SMILES:
N(c1nc(cs1)-c1ccccn1)c1ccccn1
Target:
Potassium Channel; Parasite

References

1. Bhuniya D, et al. Aminothiazoles: Hit to lead development to identify antileishmanial agents. Eur J Med Chem. 2015 Sep 18;102:582-93. 2. Skibsbye L, et al. Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium. J Cardiovasc Pharmacol. 2015 Aug;66(2):165-76.