ML402

TargetMol
Product Code: TAR-T16109
Supplier: TargetMol
CodeSizePrice
TAR-T16109-1mg1mg£95.00
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TAR-T16109-2mg2mg£106.00
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TAR-T16109-5mg5mg£128.00
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TAR-T16109-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T16109-10mg10mg£168.00
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TAR-T16109-25mg25mg£269.00
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TAR-T16109-50mg50mg£389.00
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TAR-T16109-100mg100mg£544.00
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TAR-T16109-500mg500mg£1,099.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
ML402 is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.
CAS:
298684-44-3
Formula:
C14H14ClNO2S
Molecular Weight:
295.78
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
Cc1cc(Cl)ccc1OCCNC(=O)c1cccs1
Target:
Potassium Channel

References

1. Lolicato M, et al. K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site. Nature. 2017 Jul 20;547(7663):364-368.