NS1652

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TargetMol
Product Code: TAR-T16346
Supplier: TargetMol
CodeSizePrice
TAR-T16346-1mg1mg£135.00
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TAR-T16346-5mg5mg£213.00
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Quantity:
TAR-T16346-10mg10mg£302.00
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Quantity:
TAR-T16346-25mg25mg£503.00
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Quantity:
TAR-T16346-50mg50mg£695.00
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Quantity:
TAR-T16346-100mg100mg£922.00
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Quantity:
TAR-T16346-500mg500mg£1,773.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 μM in human and mouse red blood cells.
CAS:
1566-81-0
Formula:
C15H11F3N2O3
Molecular Weight:
324.259
Pathway:
Membrane transporter/Ion channel
Purity:
0.9995
SMILES:
OC(=O)c1ccccc1NC(=O)Nc1cccc(c1)C(F)(F)F
Target:
Chloride channel

References

1. Kjaer K, et al. Chloride channel blockers inhibit iNOS expression and NO production in IFNgamma-stimulated microglial BV2 cells. Brain Res. 2009 Jul 24;1281:15-24. 2. Bennekou P, et al. Volume control in sickle cells is facilitated by the novel anion conductance inhibitor NS1652. Blood. 2000 Mar 1;95(5):1842-8.