SQ109

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TargetMol
Product Code: TAR-T16925
Supplier: TargetMol
CodeSizePrice
TAR-T16925-1mg1mg£119.00
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TAR-T16925-5mg5mg£185.00
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TAR-T16925-1mL1 mL * 10 mM (in DMSO)£198.00
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TAR-T16925-10mg10mg£254.00
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TAR-T16925-25mg25mg£462.00
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TAR-T16925-50mg50mg£643.00
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TAR-T16925-100mg100mg£863.00
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TAR-T16925-500mg500mg£1,661.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
SQ109 is an effective inhibitor of the trypomastigote form of the parasite (IC50 = 50 nM). SQ109 is an antitubercular agent and targets MmpL3.
CAS:
502487-67-4
Formula:
C22H38N2
Molecular Weight:
330.56
Pathway:
; Microbiology/Virology
Purity:
0.98
SMILES:
CC(C)=CCCC(C)=CCNCCNC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Target:
Parasite

References

1. Veiga-Santos P, et al. SQ109, a new drug lead for Chagas disease. Antimicrob Agents Chemother. 2015 Apr;59(4):1950-61. 2. Jia L, et al. Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug. Br J Pharmacol. 2005 Jan;144(1):80-7 3. Jia L, et al. Interspecies pharmacokinetics and in vitro metabolism of SQ109. Br J Pharmacol. 2006 Mar;147(5):476-85.