SAG

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TargetMol
Product Code: TAR-T1779
Supplier: TargetMol
CodeSizePrice
TAR-T1779-1mg1mg£109.00
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TAR-T1779-5mg5mg£152.00
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Quantity:
TAR-T1779-10mg10mg£197.00
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Quantity:
TAR-T1779-25mg25mg£302.00
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Quantity:
TAR-T1779-50mg50mg£393.00
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Quantity:
TAR-T1779-100mg100mg£542.00
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Quantity:
TAR-T1779-200mg200mg£744.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
SAG is a potent Smo receptor agonist and activates the Hedgehog signaling pathway.
CAS:
912545-86-9
Formula:
C28H28ClN3OS
Molecular Weight:
490.06
Pathway:
Stem Cells; GPCR/G Protein
Purity:
0.9888
SMILES:
CNC1CCC(CC1)N(Cc1cccc(c1)-c1ccncc1)C(=O)c1sc2ccccc2c1Cl
Target:
Hedgehog/Smoothened; Smo

References

1. Chen JK, et al. Proc Natl Acad Sci U S A. 2002, 99(22), 14071-14076. 2. Meloni AR, et al. Mol Cell Biol. 2006, 26(20), 7550-760. 3. Bragina O, et al. Neurosci Lett. 2010, 482(2), 81-85. 4. Heine VM, et al. Sci Transl Med. 2011, 3(105), 105ra104. 5. Schenke M, Schjeide B M, P?schel G P, et al. Analysis of Motor Neurons Differentiated from Human Induced Pluripotent Stem Cells for the Use in Cell-Based Botulinum Neurotoxin Activity Assays[J]. Toxins. 2020, 12(5): 276. 6. Schenke M. DOCTOR OF PHILOSOPHY (PhD)[D]. University of Veterinary Medicine Hannover. 2020