Siramesine hydrochloride

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TargetMol
Product Code: TAR-T1885
Supplier: TargetMol
CodeSizePrice
TAR-T1885-1mg1mg£115.00
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TAR-T1885-2mg2mg£135.00
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TAR-T1885-5mg5mg£161.00
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TAR-T1885-1mL1 mL * 10 mM (in DMSO)£169.00
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TAR-T1885-10mg10mg£217.00
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TAR-T1885-25mg25mg£369.00
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TAR-T1885-50mg50mg£517.00
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TAR-T1885-100mg100mg£699.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Siramesine (Lu 28-179) hydrochloride is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit a potent anticancer activity in vivo.
CAS:
224177-60-0
Formula:
C30H32ClFN2O
Molecular Weight:
491.05
Pathway:
Autophagy; Cell Cycle/Checkpoint; GPCR/G Protein; Apoptosis
Purity:
0.9974
SMILES:
Cl.Fc1ccc(cc1)-n1cc(CCCCN2CCC3(CC2)OCc2ccccc32)c2ccccc12
Target:
Ferroptosis; Sigma receptor; lysosomal autophagy

References

1. Cesen MH, et al. Cell Death Dis. 2013 Oct 3;4:e818.