Cinaciguat

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TargetMol
Product Code: TAR-T1984
Supplier: TargetMol
CodeSizePrice
TAR-T1984-1mg1mg£124.00
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TAR-T1984-2mg2mg£148.00
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TAR-T1984-5mg5mg£189.00
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TAR-T1984-1mL1 mL * 10 mM (in DMSO)£217.00
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TAR-T1984-10mg10mg£269.00
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TAR-T1984-25mg25mg£406.00
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TAR-T1984-50mg50mg£568.00
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TAR-T1984-100mg100mg£780.00
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TAR-T1984-500mg500mg£1,500.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Cinaciguat (BAY 58-2667) is the first of a new class of soluble guanylate cyclase (sGC) activators in Clinicalal development for acute decompensated heart failure.
CAS:
329773-35-5
Formula:
C36H39NO5
Molecular Weight:
565.71
Pathway:
GPCR/G Protein
Purity:
0.9982
SMILES:
OC(=O)CCCCN(CCc1ccccc1OCc1ccc(CCc2ccccc2)cc1)Cc1ccc(cc1)C(O)=O
Target:
Guanylate cyclase

References

1. The soluble guanylate cyclase activator cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus[J]. Cardiovascular Diabetology, 2015, 14(1):145. 2. Reinke Y, et al. The soluble guanylate cyclase stimulator riociguat and the soluble guanylate cyclase activator cinaciguat exert no direct effects on contractility and relaxation of cardiac myocytes from normal rats. Format: AbstractSend to Eur J Pharmaco 3. Cosyns SM, et al. Influence of cinaciguat on gastrointestinal motility in apo-sGC mice. Neurogastroenterol Motil. 2014 Nov;26(11):1573-85.