TargetMol

Dicentrine, (-)-

Product Code:
 
TAR-T20225
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T20225-50mg50mgEnquire
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TAR-T20225-1mg1mg£189.00
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TAR-T20225-2mg2mg£230.00
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TAR-T20225-5mg5mg£309.00
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TAR-T20225-10mg10mg£422.00
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TAR-T20225-25mg25mg£651.00
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Further Information

Bioactivity:
Dicentrine, (-)- is an aporphinic alkaloid found in several plant species, which showed significant antinociceptive activity in an acute model of visceral pain in mice.
CAS:
28832-07-7
Formula:
C20H21NO4
Molecular Weight:
339.391
Purity:
0.98
SMILES:
[H][C@]12Cc3cc(OC)c(OC)cc3-c3c4OCOc4cc(CCN1C)c23

References

1. Tiwari S, Awasthi M, Singh S, Pandey VP, Dwivedi UN. Modulation of interaction of mutant TP53 and wild type BRCA1 by alkaloids: a computational approach towards targeting protein-protein interaction as a futuristic therapeutic intervention strategy for breast cancer impediment. J Biomol Struct Dyn. 2017 Oct 23:1-12. doi: 10.1080/07391102.2017.1388286. [Epub ahead of print] PubMed PMID: 28978265. 2. Ma P, Li T, Ji F, Wang H, Pang J. Effect of GABA on blood pressure and blood dynamics of anesthetic rats. Int J Clin Exp Med. 2015 Aug 15;8(8):14296-302. eCollection 2015. PubMed PMID: 26550413; PubMed Central PMCID: PMC4613098. 3. Lin HF, Huang HL, Liao JF, Shen CC, Huang RL. Dicentrine Analogue-Induced G2/M Arrest and Apoptosis through Inhibition of Topoisomerase II Activity in Human Cancer Cells. Planta Med. 2015 Jul;81(10):830-7. doi: 10.1055/s-0035-1546128. Epub 2015 Jul 9. PubMed PMID: 26158522. 4. Dong JW, Cai L, Fang YS, Xiao H, Li ZJ, Ding ZT. Proaporphine and aporphine alkaloids with acetylcholinesterase inhibitory activity from Stephania epigaea. Fitoterapia. 2015 Jul;104:102-7. doi: 10.1016/j.fitote.2015.05.019. Epub 2015 May 29. PubMed PMID: 26028544.