ETP-46464

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TargetMol
Product Code: TAR-T2084
Supplier: TargetMol
CodeSizePrice
TAR-T2084-2mg2mg£98.00
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TAR-T2084-5mg5mg£115.00
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TAR-T2084-1mL1 mL * 10 mM (in DMSO)£119.00
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TAR-T2084-10mg10mg£142.00
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TAR-T2084-25mg25mg£213.00
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TAR-T2084-50mg50mg£303.00
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TAR-T2084-100mg100mg£442.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).
CAS:
1345675-02-6
Formula:
C30H22N4O2
Molecular Weight:
470.532
Pathway:
PI3K/Akt/mTOR signaling; DNA Damage/DNA Repair
Purity:
0.9956
SMILES:
CC(C)(C#N)c1ccc(cc1)N1C(=O)OCc2cnc3ccc(cc3c12)-c1cnc2ccccc2c1
Target:
ATM/ATR; DNA-PK; PI3K; mTOR

References

1. Toledo LI, et al. Nat Struct Mol Biol, 2011, 18(6), 721-727.