AF-353

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TargetMol
Product Code: TAR-T2087
Supplier: TargetMol
CodeSizePrice
TAR-T2087-1mg1mg£95.00
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TAR-T2087-2mg2mg£106.00
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TAR-T2087-5mg5mg£127.00
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TAR-T2087-1mL1 mL * 10 mM (in DMSO)£132.00
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TAR-T2087-10mg10mg£172.00
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TAR-T2087-25mg25mg£275.00
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TAR-T2087-50mg50mg£356.00
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TAR-T2087-100mg100mg£495.00
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TAR-T2087-500mg500mg£978.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
AF-353, an effective and orally bioavailable antagonist of the P2X3/P2X2/3 receptor, inhibits human and rat P2X3 (pIC50= 8.0).
CAS:
865305-30-2
Formula:
C14H17IN4O2
Molecular Weight:
400.22
Pathway:
Membrane transporter/Ion channel; Neuroscience
Purity:
0.9881
SMILES:
COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1I
Target:
P2X Receptor

References

1. Gever JR, et al. Br J Pharmacol. 2010 Jul;160(6):1387-1398.