AICAR monophosphate

TargetMol
Product Code: TAR-T21195
Supplier: TargetMol
CodeSizePrice
TAR-T21195-1mg1mg£142.00
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TAR-T21195-2mg2mg£173.00
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TAR-T21195-5mg5mg£246.00
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TAR-T21195-1mL1 mL * 10 mM (in DMSO)£253.00
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TAR-T21195-10mg10mg£332.00
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TAR-T21195-25mg25mg£510.00
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TAR-T21195-50mg50mg£695.00
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TAR-T21195-100mg100mg£922.00
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Quantity:
TAR-T21195-500mg500mg£1,773.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
AICAR monophosphate is a purine precursor with antineoplastic activity and can be used in studies about type 2 diabetes.
CAS:
3031-94-5
Formula:
C9H15N4O8P
Molecular Weight:
338.21
Purity:
0.9841
SMILES:
NC=1N(C=NC1C(N)=O)[C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O

References

1. Zhang M, et al. Attenuated succinate accumulation relieves neuronal injury induced by hypoxia in neonatal mice. Cell Death Discov. 2022 Mar 28;8(1):138. 2. Ye H, et al. AMPK activation overcomes anti-EGFR antibody resistance induced by KRAS mutation in colorectal cancer. Cell Commun Signal. 2020 Jul 23;18(1):115. 3. Baek SY, et al. Hemistepsin A Inhibits Cell Proliferation and Induces G0/G1-Phase Arrest, Cellular Senescence and Apoptosis Via the AMPK and p53/p21 Signals in Human Hepatocellular Carcinoma. Biomolecules. 2020 May 4;10(5):713. 4. Jin K, et al. Activation of AMP-activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic fitness. FASEB J. 2020 May;34(5):7036-7057. 5. Wang X, Xu S, Zhang L, et al. Vitamin C induces ferroptosis in anaplastic thyroid cancer cells by ferritinophagy activation[J]. Biochemical and Biophysical Research Communications. 2021, 551: 46-53.