INCA-6

TargetMol
Product Code: TAR-T21807
Supplier: TargetMol
CodeSizePrice
TAR-T21807-5mg5mg£111.00
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TAR-T21807-1mL1 mL * 10 mM (in DMSO)£136.00
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Quantity:
TAR-T21807-10mg10mg£140.00
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TAR-T21807-25mg25mg£209.00
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TAR-T21807-50mg50mg£337.00
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Quantity:
TAR-T21807-100mg100mg£525.00
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Quantity:
TAR-T21807-500mg500mg£1,058.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
INCA-6 is an inhibitor of Nuclear factor of activated T cells (NFAT) and calcineurin-NFAT signaling.
CAS:
3519-82-2
Formula:
C20H12O2
Molecular Weight:
284.31
Purity:
0.9988
SMILES:
O=C1C=CC(=O)C2=C1C3C=4C=CC=CC4C2C=5C=CC=CC53

References

1. Colin A Bretz,?et al. The role of the NFAT signaling pathway in retinal neovascularization. Invest Ophthalmol Vis Sci.?2013 Oct 25;54(10):7020-7. 2. Ling Xiao,?et al. Mechanisms underlying rate-dependent remodeling of transient outward potassium current in canine ventricular myocytes. Circ Res.?2008 Sep 26;103(7):733-42. 3. Miho Shiratori,et al. P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways. J Neurochem.?2010 Aug;114(3):810-9. 4. Anand Mohan Prasad,?et al. Silencing calcineurin A subunit reduces SERCA2 expression in cardiac myocytes. Am J Physiol Heart Circ Physiol.?2011 Jan;300(1):H173-80.