TargetMol

Gedunin

Product Code:
 
TAR-T21883
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21883-1mg1mg£402.00
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TAR-T21883-5mg5mg£1,058.00
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TAR-T21883-1mL1 mL * 10 mM (in DMSO)£1,155.00
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TAR-T21883-10mg10mg£1,420.00
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TAR-T21883-25mg25mg£2,070.00
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TAR-T21883-50mg50mg£2,769.00
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Quantity:
TAR-T21883-100mg100mg£3,709.00
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This product comes from: United States.
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Further Information

Bioactivity:
Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Gedunin is an Hsp90 inhibitor, and inhibits ovarian cancer cell proliferation.
CAS:
2753-30-2
Formula:
C28H34O7
Molecular Weight:
482.573
Pathway:
Cytoskeletal Signaling; Metabolism
Purity:
0.9968
SMILES:
CC(=O)O[C@H]1C[C@@H]2C(C)(C)C(=O)C=C[C@]2(C)[C@@H]2CC[C@@]3(C)[C@H](OC(=O)[C@H]4O[C@@]34[C@@]12C)c1ccoc1
Target:
HSP

References

1. Subramani R , Gonzalez E , Nandy S B , et al. Gedunin inhibits pancreatic cancer by altering sonic hedgehog signaling pathway[J]. Oncotarget, 2016, 8(7). 2. Ah A , D E , Rh C , et al. Hsp90 inhibitor gedunin causes apoptosis in A549 lung cancer cells by disrupting Hsp90:Beclin-1:Bcl-2 interaction and downregulating autophagy[J]. Life Sciences, 2020, 256.