SR18662

Contact us
TargetMol
Product Code: TAR-T22429
Supplier: TargetMol
CodeSizePrice
TAR-T22429-1mg1mg£103.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T22429-5mg5mg£148.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T22429-1mL1 mL * 10 mM (in DMSO)£156.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T22429-10mg10mg£201.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T22429-25mg25mg£334.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T22429-50mg50mg£495.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T22429-100mg100mg£678.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T22429-200mg200mg£863.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T22429-500mg500mg£1,299.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Documents

Further Information

Bioactivity:
SR18662, an optimized compund based on ML264 that inhibits Kr?ppel-like factor 5 (KLF5) with IC50 of 4.4 nM, reduces the viability of multiple colorectal cancer cell lines and induces apoptosis.
CAS:
T22429
Formula:
C16H19Cl2N3O4S
Molecular Weight:
420.31
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Purity:
0.9675
SMILES:
ClC1=C(Cl)C=C(/C=C/C(NCC(N2CCN(S(=O)(C)=O)CC2)=O)=O)C=C1
Target:
DNA/RNA Synthesis

References

1. Julie Kim, et al. Mol Cancer Ther. 2019 Nov;18(11):1973-1984.