FR 122047 hydrochloride
Code | Size | Price |
---|
TAR-T22790-1mg | 1mg | £106.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T22790-5mg | 5mg | £155.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T22790-10mg | 10mg | £212.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T22790-25mg | 25mg | £359.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T22790-50mg | 50mg | £535.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T22790-100mg | 100mg | £736.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 ?M for human recombinant COX-1 and COX-2, respectively.
CAS:
130717-51-0
Formula:
C23H25N3O3S?HCl
Molecular Weight:
459.99
Pathway:
Immunology/Inflammation; Neuroscience
Purity:
0.9963
SMILES:
O=C(C1=NC(C(C=C2)=CC=C2OC)=C(C(C=C3)=CC=C3OC)S1)N4CCN(C)CC4.Cl
Target:
COX
References
1. Restrepo B, Garc?a M, L?pez C, Mart?n ML, San Rom?n L, Mor?n A. The cyclooxygenase and nitric oxide synthesis/pathways mediate the inhibitory serotonergic response to the pressor effect elicited by sympathetic stimulation in long-term diabetic pithed rats. Pharmacology. 2012;90(3-4):169-76.
2. Sandberg M, Jansson L. Effects of cyclooxygenase inhibition on insulin release and pancreatic islet blood flow in rats. Ups J Med Sci. 2014 Nov;119(4):316-23.
3. Restrepo B, Garc?a M, Rodr?guez-Barbero A, Rom?n LS, Martin ML, Mor?n A. Participation of cyclooxygenase pathway in the vasoconstriction induced by 5-HT in the in situ autoperfused kidney of long-term diabetic rats. Eur J Pharmacol. 2011 May 20;659(1):37-44.