GSK2256098

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TargetMol
Product Code: TAR-T2281
Supplier: TargetMol
CodeSizePrice
TAR-T2281-1mg1mg£102.00
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TAR-T2281-2mg2mg£115.00
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TAR-T2281-1mL1 mL * 10 mM (in DMSO)£136.00
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Quantity:
TAR-T2281-5mg5mg£136.00
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Quantity:
TAR-T2281-10mg10mg£182.00
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Quantity:
TAR-T2281-25mg25mg£292.00
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Quantity:
TAR-T2281-50mg50mg£450.00
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TAR-T2281-100mg100mg£629.00
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Quantity:
TAR-T2281-500mg500mg£1,251.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
GSK-2256098 is a small molecule FAK kinase inhibitor.
CAS:
1224887-10-8
Formula:
C20H23ClN6O2
Molecular Weight:
414.89
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors; Cytoskeletal Signaling; Apoptosis
Purity:
0.9952
SMILES:
CONC(=O)c1ccccc1Nc1cc(Nc2cc(C)nn2C(C)C)ncc1Cl
Target:
Apoptosis; FAK

References

1. Zhang J, et al. Cell Cycle. 2014, 13(19):3143-9. 2. Paul Mulholland, et al. Neuro Oncol. 2015, 17(Suppl 5): v11. 3. Soria JC, et al. Ann Oncol. 2016, 27(12):2268-2274. 4. Thanapprapasr D, et al. Mol Cancer Ther. 2015, 14(6):1466-75. 5. Auger KR, et al. Eur J Cancer. 2012, 48:118