PTP1B-IN-4
| Code | Size | Price |
|---|
| TAR-T24073-50mg | 50mg | £870.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24073-100mg | 100mg | £1,468.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
PTP1B-IN-4 is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes.
CAS:
765317-72-4
Formula:
C26H19Br2N3O7S3
Molecular Weight:
741.45
Pathway:
Metabolism
Purity:
0.98
SMILES:
CCc1oc2cc(ccc2c1C(=O)c1cc(Br)c(O)c(Br)c1)S(O)(=O)=O
Target:
Phosphatase
References
1. Steinhauer J, et al. Drosophila lysophospholipid acyltransferases are specifically required for germ cell development. Mol Biol Cell. 2009 Dec;20(24):5224-35.
2. Leblanc MR, Johnson CE, Wilson PW. Influence of pressing method on juice stilbene content in muscadine and bunch grapes. J Food Sci. 2008 May;73(4):H58-62.
3. Wiesmann, C., et al. Allosteric inhibition of protein tyrosine phosphatase 1B. Nature Structural & Molecular Biology, 2004. 11(8), 730?737.
4. Jin, T., et al. Selective binding modes and allosteric inhibitory effects of lupane triterpenes on protein tyrosine phosphatase 1B. Scientific Reports, 2016. 6(1).