A66

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TargetMol
Product Code: TAR-T2418
Supplier: TargetMol
CodeSizePrice
TAR-T2418-1mg1mg£98.00
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TAR-T2418-2mg2mg£108.00
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TAR-T2418-5mg5mg£132.00
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TAR-T2418-1mL1 mL * 10 mM (in DMSO)£139.00
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Quantity:
TAR-T2418-10mg10mg£173.00
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Quantity:
TAR-T2418-25mg25mg£267.00
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Quantity:
TAR-T2418-50mg50mg£417.00
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TAR-T2418-100mg100mg£584.00
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TAR-T2418-500mg500mg£1,139.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
A66 is a specific and effective p110α inhibitor(IC50=32 nM).
CAS:
1166227-08-2
Formula:
C17H23N5O2S2
Molecular Weight:
393.52
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.9933
SMILES:
Cc1nc(NC(=O)N2CCC[C@H]2C(N)=O)sc1-c1csc(n1)C(C)(C)C
Target:
PI3K

References

1. Jamieson S, et al. Biochem J, 2011, 438(1), 53-62. 2. Sun M, et al. Proc Natl Acad Sci U S A, 2010, 107(35), 15547-15552. 3. Smith GC, et al. Biochem J, 2012, 442(1), 161-169.