MK-0752

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TargetMol
Product Code: TAR-T2625
Supplier: TargetMol
CodeSizePrice
TAR-T2625-1mg1mg£114.00
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TAR-T2625-2mg2mg£148.00
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TAR-T2625-5mg5mg£209.00
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TAR-T2625-1mL1 mL * 10 mM (in DMSO)£217.00
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TAR-T2625-10mg10mg£279.00
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TAR-T2625-25mg25mg£445.00
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TAR-T2625-50mg50mg£619.00
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TAR-T2625-100mg100mg£852.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).
CAS:
471905-41-6
Formula:
C21H21ClF2O4S
Molecular Weight:
442.9
Pathway:
Neuroscience; Stem Cells; Proteases/Proteasome
Purity:
0.9919
SMILES:
OC(=O)CC[C@H]1CC[C@@](CC1)(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1
Target:
Beta Amyloid; Gamma-secretase

References

1. Cook JJ, et al. J Neurosci, 2010, 30(19), 6743-6750. 2. Harrison H, et al. Cancer Res, 2010, 70(2), 709-718.