RI-2

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TargetMol
Product Code: TAR-T2628
Supplier: TargetMol
CodeSizePrice
TAR-T2628-1mg1mg£124.00
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TAR-T2628-2mg2mg£149.00
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TAR-T2628-5mg5mg£201.00
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TAR-T2628-1mL1 mL * 10 mM (in DMSO)£213.00
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TAR-T2628-10mg10mg£308.00
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TAR-T2628-25mg25mg£438.00
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TAR-T2628-50mg50mg£611.00
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TAR-T2628-100mg100mg£840.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
RI-2 is an optimized RAD51 inhibitor with an IC50 of 44.17 μM in the standard DNA binding assay; specifically inhibits HR(Homologous recombination) repair in human cells.
CAS:
1417162-36-7
Formula:
C21H18Cl2N2O4
Molecular Weight:
433.29
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Purity:
0.9986
SMILES:
COc1ccc(cc1)C1=C(N2CCOCC2)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1
Target:
DNA/RNA Synthesis

References

1. Budke B, et al. J Med Chem. 2013 Jan 10;56(1):254-63.