TargetMol

Chrysotoxine

Product Code:
 
TAR-T27012
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27012-1mg1mg£177.00
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TAR-T27012-1mL1 mL * 10 mM (in DMSO)£309.00
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TAR-T27012-5mg5mg£310.00
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TAR-T27012-10mg10mg£434.00
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TAR-T27012-25mg25mg£670.00
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TAR-T27012-50mg50mg£914.00
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Further Information

Bioactivity:
Chrysotoxine inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via NF-κB modulation and mitochondria protection.
CAS:
156951-82-5
Formula:
C18H22O5
Molecular Weight:
318.369
Pathway:
NF-κb
Purity:
0.9934
SMILES:
COc1cc(CCc2ccc(OC)c(OC)c2)cc(OC)c1O
Target:
NF-κB

References

1. Bhummaphan N, Pongrakhananon V, Sritularak B, Chanvorachote P. Cancer Stem Cell Suppressing Activity of Chrysotoxine, a bibenzyl from Dendrobium pulchellum. J Pharmacol Exp Ther. 2017 Dec 7. pii: jpet.117.244467. doi: 10.1124/jpet.117.244467. 2. Fan J, Guan L, Kou Z, Feng F, Zhang Y, Liu W. Determination of chrysotoxine in rat plasma by liquid chromatography-tandem mass spectrometry and its application to a rat pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Sep 15;967:57-62. doi: 10.1016/j.jchromb.2014.07.011. Epub 2014 Jul 16. 3. Chanvorachote P, Kowitdamrong A, Ruanghirun T, Sritularak B, Mungmee C, Likhitwitayawuid K. Anti-metastatic activities of bibenzyls from Dendrobium pulchellum. Nat Prod Commun. 2013 Jan;8(1):115-8. PubMed PMID: 23472473. 4. Song JX, Shaw PC, Wong NS, Sze CW, Yao XS, Tang CW, Tong Y, Zhang YB. Chrysotoxine, a novel bibenzyl compound selectively antagonizes MPP?, but not rotenone, neurotoxicity in dopaminergic SH-SY5Y cells. Neurosci Lett. 2012 Jul 11;521(1):76-81. doi: 10.1016/j.neulet.2012.05.063. Epub 2012 Jun 1. PubMed PMID: 22659498.