EF24

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TargetMol
Product Code: TAR-T27242
Supplier: TargetMol
CodeSizePrice
TAR-T27242-1mg1mg£97.00
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TAR-T27242-5mg5mg£132.00
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TAR-T27242-1mL1 mL * 10 mM (in DMSO)£138.00
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Quantity:
TAR-T27242-10mg10mg£177.00
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Quantity:
TAR-T27242-25mg25mg£298.00
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Quantity:
TAR-T27242-50mg50mg£436.00
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TAR-T27242-100mg100mg£610.00
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TAR-T27242-500mg500mg£1,219.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
EF24 treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPK/ERK signaling pathway.
CAS:
342808-40-6
Formula:
C19H15F2NO
Molecular Weight:
311.33
Pathway:
MAPK; Proteases/Proteasome; Apoptosis
Purity:
1
SMILES:
O=C1C(=CC=2C=CC=CC2F)CNCC1=CC=3C=CC=CC3F
Target:
ERK; MEK; Caspase

References

1. Lelli D, Pedone C, Sahebkar A. Curcumin and treatment of melanoma: The potential role of microRNAs. Biomed Pharmacother. 2017 Apr;88:832-834. 2. Mosley CA, Liotta DC, Snyder JP. Highly active anticancer curcumin analogues. Adv Exp Med Biol. 2007;595:77-103.