TargetMol

Euphorbia factor L1

Product Code:
 
TAR-T2S0410
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2S0410-1mL1 mL * 10 mM (in DMSO)£135.00
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Quantity:
TAR-T2S0410-20mg20mg£151.00
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Further Information

Bioactivity:
1. Euphorbia factor L1 can enhance the ATP hydrolysis activity of ABCB1 stimulated by verapamil. 2. Euphorbia factor L1 inhibits the efflux of ABCB1 in KBv200 and MCF-7/adr cells, does not downregulate their expression either in mRNA or protein level.
CAS:
76376-43-7
Formula:
C32H40O8
Molecular Weight:
552.664
Pathway:
Membrane transporter/Ion channel; Apoptosis; Neuroscience
Purity:
0.98
SMILES:
C[C@H]1C[C@@]2(OC(C)=O)[C@H]([C@H]1OC(=O)Cc1ccccc1)[C@@H](OC(C)=O)[C@@]1(CO1)CC[C@H]1[C@@H](C=C(C)C2=O)C1(C)C
Target:
Apoptosis; P-gp

References

1. Park SJ, et al. Euphorbiasteroid, a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3-L1 cells via activation of AMP-activated protein kinase.Cell Biochem Funct. 2015, 33(4):220-5. 2. Jung Sook Choi, et al. Euphorbiasteroid reverses P?glycoprotein?mediated multi?drug resistance in human sarcoma cell line MES?SA/Dx5.Phytotherapy research. 2010, 24(7):1042-1046.