Ponicidin
Code | Size | Price |
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TAR-T2S1975-25mg | 25mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2S1975-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2S1975-1mg | 1mg | £122.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2S1975-5mg | 5mg | £189.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2S1975-10mg | 10mg | £246.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2S1975-1mL | 1 mL * 10 mM (in DMSO) | £309.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Ponicidin is a diterpenoid derived from Rabdosia rubescens. Ponicidin exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer activity. Ponicidin induces apoptosis of gastric carcinoma cells, decreases the phosphorylation of JAK2 and STAT3, and shows no effect on protein levels of JAK2 and STAT3.
CAS:
52617-37-5
Formula:
C20H26O6
Molecular Weight:
362.42
Pathway:
JAK/STAT signaling; Stem Cells; Angiogenesis; Chromatin/Epigenetic; Apoptosis
Purity:
0.9992
SMILES:
C=C1C([C@@]23[C@](O)(O4)[C@@H](O)[C@]5([H])C(C)(C)CC[C@H](O)[C@@]5([C@@]4([H])O[C@@]3([H])[C@H]1CC6)[C@@]26[H])=O
Target:
Apoptosis; JAK; STAT
References
1. Xiaodan Liu, et al. Apoptosis inducing effect of ponicidin in leukemia K562 cells and its mechanisms of action. Zhongguo Zhong Yao Za Zhi. 2010 Aug;35(16):2161-5.
2. Ponicidin inhibits monocytic leukemia cell growth by induction of apoptosis. Int J Mol Sci. 2008 Nov;9(11):2265-77.