TargetMol

DY268

Product Code:
 
TAR-T31587
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31587-1mg1mg£98.00
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TAR-T31587-5mg5mg£135.00
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TAR-T31587-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T31587-10mg10mg£173.00
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TAR-T31587-25mg25mg£278.00
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TAR-T31587-50mg50mg£454.00
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TAR-T31587-100mg100mg£624.00
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TAR-T31587-500mg500mg£1,259.00
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Further Information

Bioactivity:
DY-268 is a compound based on trisubstituted pyrazolamide without any FXR agonist activity and cytotoxicity and can be used as an effective FXR antagonist (IC50 = 7.5 nM).
CAS:
1609564-75-1
Formula:
C30H32N4O5S
Molecular Weight:
560.67
Pathway:
Metabolism
Purity:
0.98
SMILES:
COc1cccc(Cn2cc(C(=O)Nc3ccc(C)c(c3)S(=O)(=O)N3CCOCC3)c(n2)-c2ccc(C)cc2)c1
Target:
FXR

References

1. Roman-Lopez J, Correcher V, Garcia-Guinea J, Prado-Herrero P, Rivera T, Lozano IB. Effect of the chemical impurities on the luminescence emission of natural apatites. Spectrochim Acta A Mol Biomol Spectrosc. 2014 May 21;126:142-7. doi: 10.1016/j.saa.2014.01.128. Epub 2014 Feb 7. PubMed PMID: 24594886. 2. Zhang Y, Popov AA, Schiemenz S, Dunsch L. Synthesis, isolation, and spectroscopic characterization of holmium-based mixed-metal nitride clusterfullerenes: HoxSc3-xN@C80 (x=1, 2). Chemistry. 2012 Jul 27;18(31):9691-8. doi: 10.1002/chem.201200574. Epub 2012 Jun 28. PubMed PMID: 22745152. 3. Evans WJ, Lee DS, Ziller JW. Reduction of dinitrogen to planar bimetallic M2(mu-eta 2:eta 2-N2) complexes of Y, Ho, Tm, and Lu using the K/Ln[N(SiMe3)2]3 reduction system. J Am Chem Soc. 2004 Jan 21;126(2):454-5. PubMed PMID: 14719928. 4. Hosoya Y. Five-year color changes of light-cured resin composites: influence of light-curing times. Dent Mater. 1999 Jul;15(4):268-74. PubMed PMID: 10551095.