TargetMol

BACE-IN-1 acetate

Product Code:
 
TAR-T3161L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-T3161L-1mg1mg£189.00
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TAR-T3161L-5mg5mg£340.00
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TAR-T3161L-10mg10mg£470.00
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TAR-T3161L-25mg25mg£707.00
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Quantity:
TAR-T3161L-50mg50mg£978.00
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This product comes from: United States.
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Further Information

Bioactivity:
β-Secretase inhibitor has been used as β-site amyloid precursor protein (APP) cleaving enzyme-1 (BACE1) inhibitor in BACE1 inhibitor assay. β-Site amyloid precursor protein (APP) cleaving enzyme-1 (BACE1), an aspartic protease belongs to the protease family of enzymes comprises of six luminal cysteine residues. These residues help in the formation of three intermolecular disulfide bonds and N-linked glycosylation sites.
CAS:
0
Formula:
C75H122N16O29
Molecular Weight:
1711.86
Pathway:
Neuroscience
Purity:
0.9698
SMILES:
O=C(O)[C@H](CC1=CC=CC=C1)NC([C@H](CCC(O)=O)NC([C@H](C)NC([C@H](C(C)C)N(C([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(C[C@H](O)[C@@H](N)CC(C)C)=O)=O)=O)=O.CC(O)=O
Target:
BACE

References

1. Yan R. Physiological Functions of the ?-Site Amyloid Precursor Protein Cleaving Enzyme 1 and 2. Front Mol Neurosci. 2017 Apr 19;10:97. doi: 10.3389/fnmol.2017.00097. PMID: 28469554; PMCID: PMC5395628.