Midostaurin

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TargetMol
Product Code: TAR-T3211
Supplier: TargetMol
CodeSizePrice
TAR-T3211-1mg1mg£108.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-T3211-5mg5mg£135.00
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TAR-T3211-1mL1 mL * 10 mM (in DMSO)£148.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3211-10mg10mg£173.00
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Quantity:
TAR-T3211-25mg25mg£254.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3211-50mg50mg£348.00
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Quantity:
TAR-T3211-100mg100mg£483.00
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TAR-T3211-500mg500mg£994.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
PKC412(Midostaurin; CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors.
CAS:
120685-11-2
Formula:
C35H30N4O4
Molecular Weight:
570.649
Pathway:
Chromatin/Epigenetic; Cytoskeletal Signaling;
Purity:
0.9956
SMILES:
CO[C@@H]1[C@@H](C[C@@H]2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1
Target:
PKC

References

1. Fabbro D, et al. Pharmacol Ther, 1999, 82(2-3), 293-301. 2. Ikegami Y, et al. Jpn J Pharmacol, 1996, 70(1), 65-72.