Leucomycin a5
| Code | Size | Price |
|---|
| TAR-T32669-1mg | 1mg | £319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T32669-5mg | 5mg | £880.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Leucomycin a5 is a metabolite from the leucomycin complex, which was originally isolated from S. kitasatoensis. It is active against a variety of Gram-positive and Gram-negative bacteria (MICs = 0.04-0.8 ?g/ml) but not against K. pneumoniae, S. typhimurium, or E. coli with MICs ranging from 5 to >10 ?g/ml. Leucomycin A5 is also active against penicillin-susceptible and -resistant S. pyogenes (MICs = 0.8 and 3.2 ?g/ml, respectively) and S. faecalis (MIC = 0.8 ?g/ml).
CAS:
18361-45-0
Formula:
C39H65NO14
Molecular Weight:
771.942
Purity:
0.98
SMILES:
CCCC(=O)O[C@H]1[C@H](C)O[C@H](C[C@@]1(C)O)O[C@@H]1[C@@H](C)O[C@@H](O[C@H]2[C@@H](CC=O)C[C@@H](C)[C@@H](O)C=C/C=C/C[C@@H](C)OC(=O)C[C@@H](O)[C@@H]2OC)[C@H](O)[C@H]1N(C)C
References
1. Yamashita K, Kinoshita K. X-ray crystallographies of leucomycin A5 and rokitamycin monomethylacetal. J Antibiot (Tokyo). 1997 Nov;50(11):975-8. PubMed PMID: 9592575.
2. Hu M, Hu CQ. [Identification of the components and products of hydrolysis in acetylleucomycin by LC-MS]. Yao Xue Xue Bao. 2006 May;41(5):476-80. Chinese. PubMed PMID: 16848328.