Momordin Ic
| Code | Size | Price |
|---|
| TAR-T3410-1mL | 1 mL * 10 mM (in DMSO) | £135.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T3410-20mg | 20mg | £135.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Momordin Ic might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways. Also, Momordin Ic accelerates gastrointestinal transit partially by stimulating synthesis of 5-HT to act through 5-HT(2), which, in turn, increases synthesis of prostaglandins.
CAS:
96990-18-0
Formula:
C41H64O13
Molecular Weight:
764.95
Pathway:
Apoptosis; MAPK; PI3K/Akt/mTOR signaling
Purity:
0.9961
SMILES:
CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H]([C@H](O)[C@@H](O[C@H]7OC[C@H](O)[C@@H](O)[C@@H]7O)[C@@H]6O)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O
Target:
Apoptosis; MAPK; PI3K
References
Li Y, et al. Eur J Pharmacol. 2000 Mar 24;392(1-2):71-7.
Wang J, et al. Apoptosis. 2013 Jun;18(6):751-65.
Matsuda H, et al. J Pharmacol Exp Ther. 1999 May;289(2):729-34.
Kim NY, et al. J Med Food. 2005 Summer;8(2):177-83.