CA-074 methyl ester

TargetMol
Product Code: TAR-T3420
Supplier: TargetMol
CodeSizePrice
TAR-T3420-1mg1mg£114.00
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TAR-T3420-2mg2mg£128.00
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TAR-T3420-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T3420-5mg5mg£164.00
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TAR-T3420-10mg10mg£230.00
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TAR-T3420-25mg25mg£389.00
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TAR-T3420-50mg50mg£544.00
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TAR-T3420-100mg100mg£748.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
CA-074 methyl ester is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.
CAS:
147859-80-1
Formula:
C19H31N3O6
Molecular Weight:
397.472
Pathway:
Proteases/Proteasome
Purity:
0.9726
SMILES:
CCCNC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)OC
Target:
Cysteine Protease

References

Wang Y, Chen Y Y, Gao G B, et al.Polyphyllin D ?Punctures? Hypertrophic Lysosomes to Reverse Drug Resistance of Hepatocellular Carcinoma by Targeting Acid Sphingomyelinase.Molecular Therapy.2023 Dietmar Steverding, et al. The Open Enzyme Inhibition Journal. 2011, 4:11-16. Jane DT, et al. Biochem Cell Biol. 2002, 80(4):457-65.