Thiomyristoyl

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TargetMol
Product Code: TAR-T3447
Supplier: TargetMol
CodeSizePrice
TAR-T3447-1mg1mg£112.00
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TAR-T3447-2mg2mg£127.00
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TAR-T3447-5mg5mg£141.00
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TAR-T3447-1mL1 mL * 10 mM (in DMSO)£172.00
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TAR-T3447-10mg10mg£172.00
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TAR-T3447-25mg25mg£262.00
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TAR-T3447-50mg50mg£393.00
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TAR-T3447-100mg100mg£550.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.
CAS:
1429749-41-6
Formula:
C34H51N3O3S
Molecular Weight:
581.86
Pathway:
DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.9913
SMILES:
CCCCCCCCCCCCCC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1
Target:
Sirtuin

References

Jing H, et al. Cancer Cell. 2016, 29(3):297-310.