TargetMol

Formosanin C

Product Code:
 
TAR-T3519
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3519-1mg1mg£122.00
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TAR-T3519-5mg5mg£195.00
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TAR-T3519-10mg10mg£229.00
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TAR-T3519-1mL1 mL * 10 mM (in DMSO)£254.00
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TAR-T3519-25mg25mg£349.00
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TAR-T3519-50mg50mg£485.00
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TAR-T3519-100mg100mg£662.00
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This product comes from: United States.
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Further Information

Bioactivity:
Polyphyllin B is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity in cultured cells and animal systems.
CAS:
50773-42-7
Formula:
C51H82O20
Molecular Weight:
1015.197
Pathway:
Apoptosis; Proteases/Proteasome
Purity:
0.9993
SMILES:
C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@@H](C)[C@H](O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H]3O)[C@H](O)[C@H]2O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)O[C@]11CC[C@@H](C)CO1
Target:
Apoptosis; Caspase

References

Lee JC., et al. Formosanin C-induced apoptosis requires activation of caspase-2 and change of mitochondrial membrane potential. Cancer Sci. 2009 Mar;100(3):503-13. Chen P, Wu S, Dong X, et al. Formosanin C induces autophagy-mediated apoptosis in multiple myeloma cells through the PI3K/AKT/mTOR signaling pathway. Hematology. 2022, 27(1): 977-986