5 α-Hydroxy-6-keto cholesterol

TargetMol
Product Code: TAR-T35236
Supplier: TargetMol
CodeSizePrice
TAR-T35236-1mg1mg£215.00
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Quantity:
TAR-T35236-10mg10mg£581.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Yakkasterone is a major metabolite of cholesterol formed during exposure of lung epithelial cells to ozone.
CAS:
13027-33-3
Formula:
C27H46O3
Molecular Weight:
418.662
Purity:
0.98
SMILES:
CC(C)CCC[C@@H](C)[C@@H]1CC[C@H]2[C@@H]3CC(=O)[C@@]4(O)C[C@@H](O)CC[C@@]4(C)[C@@H]3CC[C@]12C

References

Matsushima Y, Fukasawa H, Endo Y, Hashimoto Y, Shudo K. Enhancement of human papillomavirus type 18 gene expression in HeLa cells by 12-O-tetradecanoylphorbol-13-acetate, 3 beta,5 alpha-dihydroxycholestan-6-one, and cholesterol. Biol Pharm Bull. 1994 Sep;17(9):1292-5. PubMed PMID: 7841956. Yamaguchi M, Endo Y, Shimizu M, Yamamoto K, Yamada S, Shudo K. 3 beta,5 alpha-Dihydroxycholestan-6-one exists in human blood. Biol Pharm Bull. 1997 Sep;20(9):1044-6. PubMed PMID: 9331996. Endo Y, Hashimoto Y, Fukasawa H, Shudo K. Oxygenated cholesterols as ligands for cytosolic-nuclear tumor promoter binding protein: yakkasteroids. Biochem Biophys Res Commun. 1993 Aug 16;194(3):1529-35. PubMed PMID: 8352811.