Massarigenin C
| Code | Size | Price |
|---|
| TAR-T35798-1mg | 1mg | £338.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Massarigenin C is a fungal metabolite that has been found inM. flavoroseaand has enzyme inhibitory activities.1,2Massarigenin C inhibits neuraminidasein vitro(IC50= 4.15 μM).2It is also an inhibitor of yeast α-glucosidase (IC50= 1.25 mM).1It reduces the postprandial peak in blood glucose levels in an oral sucrose tolerance test in normo- and hyperglycemic mice when administered at doses of 3.2, 10, and 31.6 mg/kg.
CAS:
496926-08-0
Formula:
C11H12O5
Molecular Weight:
224.2
Purity:
0.98
SMILES:
O=C1C=C[C@@H](C)[C@@]2([C@@H](O)C(OC2=O)=C)[C@H]1O
References
Verastegui-Oma?a, B., Rebollar-Ramos, D., P?rez-V?squez, A., et al.?-Glucosidase inhibitors from Malbranchea flavoroseJ. Nat. Prod.80(1)190-195(2017)
Zhang, G.F., Han, W.B., Cui, J.T., et al.Neuraminidase inhibitory polyketides from the marine-derived fungus Phoma herbaruPlanta Med.78(1)76-78(2012)