D-myo-Inositol-1,4,6-triphosphate (sodium salt)
| Code | Size | Price |
|---|
| TAR-T35936-1mg | 1mg | £560.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
D-myo-Inositol-1,4,6-phosphate (Ins(1,4,6)-P3) is a member of the inositol phosphate (InsP) family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)-P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)-P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(1,4,6)-P3 (tested as the meso compound) is 9-fold less potent than Ins(1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes.
CAS:
157380-18-2
Formula:
C6H12O15P3?3Na
Molecular Weight:
486
Purity:
0.98
SMILES:
O[C@H]1[C@H](OP([O-])(O)=O)[C@@H](O)[C@@H](O)[C@@H](OP([O-])(O)=O)[C@@H]1OP([O-])(O)=O.[Na+].[Na+].[Na+]