TargetMol

4-hydroxy Nonenal Mercapturic Acid

Product Code:
 
TAR-T35971
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35971-1mg1mg£164.00
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TAR-T35971-5mg5mg£503.00
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TAR-T35971-10mg10mg£842.00
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Further Information

Bioactivity:
Peroxidation of common ?-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid can give rise to 4-HNE. 4-HNE is cleared rapidly from the plasma and undergoes enterohepatic circulation as a glutathione conjugate in the rat. About two thirds of an administered dose of 4-HNE is excreted within 48 hours in the urine, primarily in the form of mercapturic acid conjugates. The C-1 aldehyde of 4-HNE is reduced to an alcohol in about half of these metabolites. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form γ-lactols and γ-lactones, respectively, producing at least 4 or 5 end urinary metabolites of 4-HNE in vivo.
CAS:
146764-24-1
Formula:
C14H25NO5S
Molecular Weight:
319.4
Purity:
0.98
SMILES:
CCCCCC1OC(O)CC1SC[C@H](NC(=O)C)C(=O)O