Flumequine-13C3

TargetMol
Product Code: TAR-T36021
Supplier: TargetMol
CodeSizePrice
TAR-T36021-1mg1mg£275.00
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Quantity:
TAR-T36021-5mg5mg£1,001.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Flumequine-13C3is intended for use as an internal standard for the quantification of flumequine by GC- or LC-MS. Flumequine is a fluoroquinolone antibiotic.1It is active againstS. aureus, S. pyogenes, B. subtilis, E. coli, P. aeruginosa, S. faecalis, andK. pneumoniae(MICs = 1-100 μg/ml). Flumequine is also active against field isolates of B. hyodysenteriae (MICs = 6.25-200 μg/ml).2It inhibits DNA gyrase, disrupting supercoiling of bacterial DNA to block transcription and replication.3
CAS:
1185049-09-5
Formula:
C11[13C]3H12FNO3
Molecular Weight:
264.2
Purity:
0.98
SMILES:
O=[13C]1C2=CC(F)=CC3=C2N(C(CC3)C)C=[13C]1[13C](O)=O

References

Rohlfing, S.R., Gerster, J.R., and Kvam, D.C.Bioevaluation of the antibacterial flumequine for urinary tract useAntimicrob. Agents Chemother.10(1)20-24(1976) Aller-Mor?n, L.M., Mart?nez-Lobo, F.J., Rubio, P., et al.Evaluation of the in vitro activity of flumequine against field isolates of Brachyspira hyodysenteriaeRes. Vet. Sci.10351-53(2015) Smith, J.T.The mode of action of 4-quinolones and possible mechanisms of resistanceJ. Antimicrob. Chemother.18 (Suppl. D)21-29(1986)