TNF- α Antagonist
| Code | Size | Price |
|---|
| TAR-T36127-1mg | 1mg | £303.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T36127-5mg | 5mg | £1,062.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor. By blocking the TNF receptor ligand contact site, this peptide interferes with both activating receptor activator of NF-κB (RANK) and TNF-α's recruitment and activation of osteoclasts. TNF-α antagonist has been used to block bone resorption in the study of systemic bone loss in rheumatoid arthritis and inflammatory bone destruction.
CAS:
199999-60-5
Formula:
C58H71N11O15S2
Molecular Weight:
1226.4
Purity:
0.98
SMILES:
[H]N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](CC(C)C)C1=O)=O)CC2=CC=C(O)C=C2)=O)=O)=O)CC3=CNC4=C3C=CC=C4)=O)CSSC[C@H](N1)C(N[C@H](C(O)=O)CC5=CC=C(O)C=C5)=O)=O)CC6=CC=C(O)C=C6