TargetMol

8-iso Prostaglandin E2

Product Code:
 
TAR-T36160
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36160-1mg1mg£173.00
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TAR-T36160-5mg5mg£491.00
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TAR-T36160-10mg10mg£699.00
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Further Information

Bioactivity:
8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with IC50 values of 0.5 and 5 μM, respectively. When infused into the renal artery of the rat at a concentration of 4 μg/kg/min, 8-iso PGE2 decreases the GFR and renal plasma flow by 80% without affecting blood pressure.
CAS:
27415-25-4
Formula:
C20H32O5
Molecular Weight:
352.471
Purity:
0.98
SMILES:
CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@H]1CC=C/CCCC(O)=O