Burnettramic Acid A aglycone
| Code | Size | Price |
|---|
| TAR-T36337-1mg | 1mg | £650.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Burnettramic acid A aglycone is a fungal metabolite and an aglycone form of burnettramic acid A originally isolated fromA. burnettiithat has anticancer activity.1It is cytotoxic to NS-1 murine myeloma cells but not neonatal foreskin fibroblasts (IC50s = 8.4 and >100 μg/ml, respectively).
CAS:
2396676-46-1
Formula:
C35H61NO7
Molecular Weight:
607.9
Purity:
0.98
SMILES:
OCCCCCCC[C@@H](O)CCC[C@@H](O)C/C=C/CCCCCCC[C@@H](C)C[C@H](C)/C(O)=C1C([C@@]2(C[C@H](CN2C1=O)O)[H])=O
References
Li, H., Gilchrist, C.L.M., Lacey, H.J., et al.Discovery and heterologous biosynthesis of the burnettramic acids: Rare PKS-NRPS-derived bolaamphiphilic pyrrolizidinediones from an Australian fungus, Aspergillus burnettiiOrg. Lett.21(5)1287-1291(2019)