DCP-Rho1
Code | Size | Price |
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TAR-T36502-1mg | 1mg | £631.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
DCP-Rho1 is a fluorescent probe for the detection of sulfenic acid-containing proteins.1,2 It displays excitation/emission maxima of 560/581 nm, respectively, and has been used to visualize protein oxidation sites in situ.
CAS:
1001575-98-9
Formula:
C42H51N4O6.Cl
Molecular Weight:
743.3
Purity:
0.98
SMILES:
O=C(OCCCC1C(CC(CC1)=O)=O)N2CCN(C(C3=C(C4=C(C=C/5)C(OC6=CC(N(CC)CC)=CC=C64)=CC5=[N+](CC)CC)C=CC=C3)=O)CC2.[Cl-]
References
Holmila, R.J., Vance, S.A., Chen, X., et al. Mitochondria-targeted probes for imaging protein sulfenylation. Sci. Rep. 8(1), 6635 (2018).
Klomsiri, C., Rogers, L.C., Soito, L., et al. Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling. Free Rad. Biol. Med. 71, 49-60 (2014).