Rp-8-bromo-Cyclic AMPS (sodium salt)

TargetMol
Product Code: TAR-T36677
Supplier: TargetMol
CodeSizePrice
TAR-T36677-1mg1mg£401.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T36677-5mg5mg£1,555.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Further Information

Bioactivity:
Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP. It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. Rp-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II from bovine heart.
CAS:
925456-59-3
Formula:
C10H10BrN5O5PS ?Na
Molecular Weight:
446.1
Purity:
0.98
SMILES:
O[C@H]1[C@H](N2C(Br)=NC3=C2N=CN=C3N)O[C@H]4[C@H]1O[P@@](OC4)([S-])=O.[Na+]