CP21R7

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TargetMol
Product Code: TAR-T3684
Supplier: TargetMol
CodeSizePrice
TAR-T3684-1mg1mg£116.00
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TAR-T3684-1mL1 mL * 10 mM (in DMSO)£130.00
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Quantity:
TAR-T3684-2mg2mg£133.00
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Quantity:
TAR-T3684-5mg5mg£149.00
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Quantity:
TAR-T3684-10mg10mg£197.00
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Quantity:
TAR-T3684-25mg25mg£301.00
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Quantity:
TAR-T3684-50mg50mg£462.00
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Quantity:
TAR-T3684-100mg100mg£643.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
CP21R7 is an effective and specific GSK3β inhibitor. It is used as an activator of stem cells prior to the induction of differentiation of stem cells to smooth muscle and endothelial cells. CP21R7 can be combined with BMP4 to commit human pluripotent stem cells to a mesodermal fate.
CAS:
125314-13-8
Formula:
C19H15N3O2
Molecular Weight:
317.348
Pathway:
Cytoskeletal Signaling; Stem Cells; PI3K/Akt/mTOR signaling; Chromatin/Epigenetic
Purity:
0.9821
SMILES:
Cn1cc(C2=C(C(=O)NC2=O)c2cccc(N)c2)c2ccccc12
Target:
GSK-3; PKC

References

Sahara M, et al. Cell Res. 2014 Jul;24(7):820-41. Gong L, et al. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1693-6. Sahara M, et al. Cell Res. 2015 Jan;25(1):148. Patsch C, et al. Nat Cell Biol. 2015 Aug;17(8):1994-12003.