Phomopsinamine

TargetMol
Product Code: TAR-T36855
Supplier: TargetMol
CodeSizePrice
TAR-T36855-1mg1mg£1,339.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Phomopsinamine is an inhibitor of microtubule polymerization and a derivative of phomopsin A .1It inhibits the rate and extent of polymerization of tubulin isolated from ovine brain (IC50s = 0.53 and 0.59 μM, respectively).
CAS:
89085-54-1
Formula:
C32H43ClN6O8
Molecular Weight:
675.2
Purity:
0.98
SMILES:
ClC1=CC([C@H](O)[C@@H]2NC)=CC(O[C@@](CC)(C)[C@@](NC([C@H](C(C)=C)NC2=O)=O)([H])C(N3[C@@](C(N/C(C(N)=O)=C(CC)C)=O)([H])C=CC3)=O)=C1O

References

Lacey, E., Edgar, J.A., and Culvenor, C.C.Interaction of phomopsin A and related compounds with purified sheep brain tubulinBiochem. Pharmacol.36(13)2133-2138(1987)