16 α-hydroxy Dehydroepiandrosterone

TargetMol
Product Code: TAR-T36920
Supplier: TargetMol
CodeSizePrice
TAR-T36920-1mg1mg£129.00
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TAR-T36920-5mg5mg£345.00
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TAR-T36920-10mg10mg£560.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
16α-hydroxy Dehydroepiandrosterone is a metabolite of the endogenous steroid hormone dehydroepiandrosterone .116α-hydroxy Dehydroepiandrosterone is formed from dehydroepiandrosteronevia16-hydroxylation by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in adult human liver microsomes, as well as by fetal recombinant CYP3A7. It is a precursor to fetal estrogens, including estriol .2
CAS:
1232-73-1
Formula:
C19H28O3
Molecular Weight:
304.4
Purity:
0.98
SMILES:
C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)(C([C@@H](C4)O)=O)C

References

Hampl, R., and Starka, L.Minireview: 16?-Hydroxylated metabolites of dehydroepiandrosterone and their biological significanceEndocr. Regul.34(3)161-163(2000) Miller, K.K.M., Cai, J., Ripp, S.L., et al.Stereo- and regioselectivity account for the diversity of dehydroepiandrosterone (DHEA) metabolites produced by liver microsomal cytochromes P450Drug. Metab. Dispos.32(3)305-313(2004)