CAY10737
| Code | Size | Price |
|---|
| TAR-T36966-1mg | 1mg | £517.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
CAY10737 is a turn-on fluorescent probe for the detection of carbon monoxide (CO). It is selective for CO over a variety of anions, amino acids, amines, biothiols, and reactive species. In the presence of palladium (Pd) and CO, CAY10737 undergoes the Pd0-mediated Tsuji-Trost reaction to release a fluorescent compound that has absorption and emission maxima of 678/714 nm, respectively. This fluorescence can be used to detect CO production in vitro and in vivo. CAY10737 has low cytotoxicity, decreasing viability of HeLa cells by less than 25% when used at a concentration of 50 μM with PdCl2 for 24 hours.
CAS:
2079118-42-4
Formula:
C30H30NO4
Molecular Weight:
468.6
Purity:
0.98
SMILES:
C[N+]1=C(C(C)(C)C2=C1C=CC=C2)/C=C/C(CCC3)=C(C3=C4)OC5=C4C=CC(OC(OCC=C)=O)=C5
References
Feng, W., and Feng, H. A readily available colorimetric and near-infrared ?uorescent turn-on probe for detection of carbon monoxide in living cells and animals. Sens. Actuators B Chem. 255(Part 2), 2314-2320 (2018).