TargetMol

PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)

Product Code:
 
TAR-T37028
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37028-1mg1mg£1,162.00
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TAR-T37028-5mg5mg£4,663.00
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Further Information

Bioactivity:
The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates.
CAS:
1628353-02-5
Formula:
C41H78Na4O22P4
Molecular Weight:
1138.907
Purity:
0.98
SMILES:
[Na+].[Na+].[Na+].[Na+].CCCCCCCCCCCCCCCC(=O)OCC(COP([O-])(=O)OC1C(O)C(OP(O)([O-])=O)C(OP(O)([O-])=O)C(OP(O)([O-])=O)C1O)OC(=O)CCCCCCCCCCCCCCC