Polygalacic acid
| Code | Size | Price |
|---|
| TAR-T3767-1mg | 1mg | £144.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Polygalacic acid(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and elevates levels of acetylcholine (ACh) in the hippocampus and frontal cortex, PA also significantly ameliorates neuroinflammation and oxidative stress in mice; suggest that PA might exert a significant neuroprotective effect on cognitive impairment, driven in part by the modulation of cholinergic activity and neuroinflammation. Polygalacic acid shows significant postingestive effects on Spodoptera littoralis larvae.
CAS:
22338-71-2
Formula:
C30H48O6
Molecular Weight:
504.708
Pathway:
Proteases/Proteasome; Neuroscience
Purity:
0.9892
SMILES:
CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@@]34C)C2C1)C(O)=O
Target:
MMP; AChR; AChE
References
Choi YH1, Yoo DS, Cha MR, Choi CW, Kim YS, Choi SU, Lee KR, Ryu SY. J Nat Prod. 2010 Nov 29;73(11)
Hern?ndez-Carlos B1, Gonz?lez-Coloma A, Orozco-Valencia AU, Ram?rez-Mares MV, Andr?s-Yeves MF, Joseph-Nathan P.