TargetMol

Methyl protodioscin

Product Code:
 
TAR-T3771
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3771-20mg20mg£159.00
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Quantity:
TAR-T3771-1mL1 mL * 10 mM (in DMSO)£175.00
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Further Information

Bioactivity:
Methyl protodioscin potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in human A549 cells is closely associated with Mitochondrial membrane potential, caspase-3, and mitochondrial cytochrome c.
CAS:
54522-52-0
Formula:
C52H86O22
Molecular Weight:
1063.238
Pathway:
Apoptosis
Purity:
0.9957
SMILES:
CO[C@]1(CC[C@@H](C)CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O[C@H]2C[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]3(C)[C@H]2[C@@H]1C)O[C@@H]1O[C@H](CO)[C@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O
Target:
Apoptosis

References

Ma W,et al.Methyl protodioscin increases ABCA1 expression and cholesterol efflux while inhibiting gene expressions for synthesis of cholesterol and triglycerides by suppressing SREBP transcription and microRNA 33a/b levels.Atherosclerosis. 2015 Apr;239(2):566-70. Bai Y,et al.Methyl protodioscin induces G2/M cell cycle arrest and apoptosis in A549 human lung cancer cells.Pharmacogn Mag. 2014 Jul;10(39):318-24.