TargetMol

Aureusimine B

Product Code:
 
TAR-T37753
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37753-1mg1mg£189.00
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Quantity:
TAR-T37753-1mL1 mL * 10 mM (in DMSO)£306.00
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TAR-T37753-5mg5mg£340.00
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TAR-T37753-10mg10mg£470.00
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TAR-T37753-25mg25mg£707.00
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TAR-T37753-50mg50mg£978.00
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Quantity:
TAR-T37753-100mg100mg£1,291.00
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Quantity:
TAR-T37753-500mg500mg£2,456.00
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This product comes from: United States.
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Further Information

Bioactivity:
Aureusimine B, a Calpain inhibitor, is produced by Staphylococcus aureus biofilms and could be a potential biomarker for S. aureus biofilm-based infections.
CAS:
170713-71-0
Formula:
C14H16N2O
Molecular Weight:
228.295
Pathway:
Microbiology/Virology; Proteases/Proteasome
Purity:
0.98
SMILES:
CC(C)c1ncc(Cc2ccccc2)[nH]c1=O
Target:
Cysteine Protease; Antibacterial

References

Alvarez ME, et al. Phevalin, a new calpain inhibitor, from a Streptomyces sp. J Antibiot (Tokyo). 1995 Oct;48(10):1165-7. Secor PR, Jennings LK, James GA, Kirker KR, Pulcini ED, McInnerney K, Gerlach R, Livinghouse T, Hilmer JK, Bothner B, Fleckman P, Olerud JE, Stewart PS. Phevalin (aureusimine B) production by Staphylococcus aureus biofilm and impacts on human keratinocyte gene expression. PLoS One. 2012;7(7):e40973. doi: 10.1371/journal.pone.0040973. Epub 2012 Jul 13. Erratum in: PLoS One. 2012;7(10). doi:10.1371/annotation/0fc3d60c-8ae4-4f04-be17-d5d245b4eef5. PMID: 22808288; PMCID: PMC3396627. Ramesh R, et al. Synthesis of the Nonribosomal Peptide Phevalin and Analogs. J Org Chem. 2019 Mar 15;84(6):3647-3651.